In recent years, biomedical research and drug development have witnessed a profound evolution in in vitro models. Although traditional 2D cell cultures have represented the benchmark standard for decades due to their simplicity and reproducibility, they show significant limitations in replicating the complex architecture and physiology of human tissues in vivo.
The transition to three-dimensional models and organoids marks a fundamental turning point: these self-organizing 3D structures mimic the function, microanatomy, and cellular interactions of real organs, offering data with significantly higher predictive value for toxicology, pharmacology, and personalized medicine studies, while simultaneously reducing reliance on animal testing.
The LTTA Laboratory Biobank Service is pleased to announce a scientific seminar organized in collaboration with Merck, a leading global life science company. The seminar, titled "From 2D cell cultures to organoids: An overview of advantages and Merck solutions," will provide an in-depth look at the evolution of cell modeling systems and the opportunities offered by three-dimensional cultures for translational research and drug discovery.
In this seminar, key differences between 2D and 3D models will be explored, analyzing the main operational and scientific advantages of adopting organoids in laboratory workflows. A comprehensive overview of the solutions and technologies developed by Merck will also be presented.
The seminar represents an essential professional development opportunity for researchers, faculty, students, and industry professionals interested in integrating 3D cultures into their research projects and understanding the key role of biobanking services in managing these biological resources.
The event will take place on October 28, 2026, from 2:30 PM to 3:30 PM, in Room B3 of Palazzo Manfredini (first floor).